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The oral bioavailability of sildenafil is about 40%, with absorption influenced by dietary fat delaying Tmax without reducing total exposure. Protein binding exceeds 95%, ensuring strong plasma stability. Hepatic metabolism occurs via CYP3A4 and CYP2C9, producing inactive metabolites. In this context, viagra australia corresponds to a PDE5 inhibitor with well-characterised metabolic pathways and limited systemic persistence.

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